Detail Inovasi Perguruan Tinggi

Tema: Artikel Penelitian
Judul: Antibacterial activity and phytochemical screening of Kesambi (Sapindaceae) against Eschericia coli and Staphylococcus aureus
Perguruan Tinggi: Sekolah Tinggi Analis Kimia Cilegon
Jenis/sdm: dosen/0406068904

Tahun: 2019

Kesambi plant (Schleichera oleosa) is a medicinal plant belongs to family Sapindaceae, commonly found in tropical and subtropical regions of the world. In Indonesia, kesambi plants can be found in Java and Bali island. The purpose of this study is to extraction and antibacterial activity test of steam bark extract of kesambi against Escherichia coli and Staphylococcus aureus. Extraction was done by maceration method using n-hexane, ethyl acetate and methanol. Antibacerial test using Kirby bauer method by measure inhibition zone. Phytochemical screening shown that n-hexane extract contain triterpenes and steroid compounds. Ethyl acetate extract contain triterpenes, flavonoid, steroid, and fenolic compounds. Methanol extract contain flavonoid, fenolic and triterpenes compounds. Inhibition zone of n-hexane, ethyl acetate and methanol extracts against E. coli and S. aureus at concentration of 5000 μg/mL showed 4.4; 7.9; 4.6 mm and 4.7; 8.9; 4.5 respectively, while amoxicillin and ciprofloxacin as positive control at concentration of 100 μg/mL showed 6.9 and 7.1 mm respectively. Kesambi extract have potential as antibacterial against E. coli and S. aureus.