Detail Inovasi Perguruan Tinggi


Tema: Jurnal Kimia Valensi
Judul: Isolation of Triterpenoid Compound from Ethyl Acetate Extract of Pirdot (Saurauia vulcani, Kurth)
Perguruan Tinggi: Sekolah Tinggi Analis Kimia Cilegon
Jenis/sdm: dosen/0406068904

Tahun: 2018

Pirdot plant(Saurauia vulcani. Kurth)is a plant that grows naturally in a tropical climate. During this decoction

pirdot leaves plants are used by the people to treat diabetes disease. The purpose of this study was to isolate

triterpenoid compound from ethyl acetate extract of pirdot leaves. The sample extraction was performed by total

of maceration method using ethyl acetate as a solvent. The separation and purification of the compound was

carried out by column chromatography method followed by stain pattern analysis with thin layer chromatography

(TLC). Structure characterization of pure compound was determined using UV, IR, 1H-NMR, 13C-NMR, DEPT

135º, HMQC, HMBC, 1H-1H COSY and MS spectroscopies including compared with various literatures. Based

on the analysis result, the pure isolate obtained was identified as a pentacyclic triterpenoid compound, 3-hydroxy

acid, 12(13)-en,28-oleanolate acid with the molecular formula C30H48O3. The triterpenoid compound of

pentacyclic oleanolic acid is the first reported from the pirdot plant (Saurauia vulcani. Kurth).